Structural insights into aminoacyl-tRNA delivery by EF-Tu and translocation by EF-G
Audio-visual presentation: Schematic of elongation cycle -- Role of elongation factors EF-G and EF-Tu -- Molecular mimicry of elongation factors -- Binding positions of factors and tRNA during elongation cycle -- Process of tRNA selection -- Proofreading -- Role of bases A1492 and A1493 -- GTP hydrolysis on EF-Tu -- tRNA as a molecular spring -- Translocation -- Intersubunit ratchet motion -- Induced fit -- FRET studies of ratchet motion -- Hybrid states of tRNA -- Role of GTP hydrolysis in translocation.
"Audio-visual presentation: Schematic of elongation cycle -- Role of elongation factors EF-G and EF-Tu -- Molecular mimicry of elongation factors -- Binding positions of factors and tRNA during elongation cycle -- Process of tRNA selection -- Proofreading -- Role of bases A1492 and A1493 -- GTP hydrolysis on EF-Tu -- tRNA as a molecular spring -- Translocation -- Intersubunit ratchet motion -- Induced fit -- FRET studies of ratchet motion -- Hybrid states of tRNA -- Role of GTP hydrolysis in translocation."@en
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