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http://worldcat.org/entity/work/id/140748831

TNF receptor associated factors (TRAFs)

It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the interleukin-1 receptor/Toll-like receptor superfamily and the T-cell receptors. They play important roles in mammalian biology including embryonic development, innate and adaptive immune regulation and maintenance of cellular homeostasis. Agents that manipulate the signaling of these receptors are being used or showing promise towards the treatment and prevention of many human diseases such as rheumatoid arthritis, coronary heart disease.

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  • "It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the interleukin-1 receptor/Toll-like receptor superfamily and the T-cell receptors. They play important roles in mammalian biology including embryonic development, innate and adaptive immune regulation and maintenance of cellular homeostasis. Agents that manipulate the signaling of these receptors are being used or showing promise towards the treatment and prevention of many human diseases such as rheumatoid arthritis, coronary heart disease."@en

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  • "Electronic books"@en
  • "Electronic books"
  • "Aufsatzsammlung"

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  • "TNF receptor associated factors (TRAFs)"@en
  • "TNF receptor associated factors (TRAFs)"
  • "TNF Receptor Associated Factors (TRAFs)"
  • "TNF Receptor Associated Factors (TRAFs)"@en