. . "Anticancéreux Efficacité." . . "Cellules cancéreuses." . . "Nephritis, Interstitial physiopathology." . . "Antisickling Agents history." . . "Cancer Chimiothérapie Manuels de laboratoire." . . "Modèles animaux." . . "Tests de criblage d'agents antitumoraux méthodes." . . "Dumping Syndrome diagnosis." . . "Cancer Aspect moléculaire." . . . "Llibres electrònics" . . . . . . . . . . . . . . . . . . "Chemosensitivity Volume 1 In Vitro Assays" . . . . . . . "Internet Resource"@en . "Chemosensitivity. Volume 1, In vitro assays"@en . "Chemosensitivity. Vol. 1, In vitro assays"@en . "Chemosensitivity"@en . "Chemosensitivity" . . . . . . . . "In vitro assays"@en . . . . "A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Chemosensitivity, Volume 1: In Vitro Assays provides a panel of 16 in vitro measures of chemosensitivity in adherent and non-adherent cells for single agents and combinations of agents. In addition to immunohistochemical and imaging approaches, these assays include clonogenic, colorimetric, fluorometric, and physiological assays. Highlights include image analysis to assess drug sensitivity, high throughput approaches using green fluorescent protein, DIMSCAN (a microcomputer fluorescence-based assay), and the ChemoFx assay used in biotechnology. A companion volume, Volume 2: In Vivo Models, Imaging, and Molecular Regulators, provides protocols for classifying tumors into response categories and customizing chemotherapy regimens to individual patients." . . . . . "Online-Publikation" . . "Fulltext"@en . . . . . . "Chemosensitivity In Vitro Assays" . "Chemosensitivity In Vitro Assays"@en . . . . "Handbooks and manuals" . "Handbooks and manuals"@en . . . . . . . . . . . . "Chemosensitivity testing is an ex vivo means of determining or enhancing the cytotoxic and/or cytostatic, or apoptosis-inducing effects of anticancer drugs. In Chemosensitivity, leading researchers and physicians working in academia and biotech companies describe state-of-the-art laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters that modulate chemosensitivity in individual tumors. Volume 1: In Vitro Assays provides a panel of 16 in vitro measures of chemosensitivity in adherent and nonadherent cells for single agents and combinations of agents. In addition to immunohistochemical and imaging approaches, these assays include clonogenic, colorimetric, fluorometric, and physiological assays. Highlights include image analysis to assess drug sensitivity, high throughput approaches using green fluorescent protein, DIMSCAN (a microcomputer fluorescence-based assay), and the ChemoFx assay used in biotechnology. The protocols follow the successful Methods in Molecular Medicine series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. The authors also provide guidance on how best to analyze the data derived from the protocols. A companion volume, Volume 2: In Vivo Models, Imaging, and Molecular Regulators, provides protocols for classifying tumors into response categories and customizing chemotherapy regimens to individual patients. Cutting-edge and highly practical, the two volumes of Chemosensitivity provide a comprehensive collection of readily reproducible techniques for the in vitro and in vivo screening of new agents and a set of proven approaches to understand mechanistically why certain cancer cell lines (in vitro) of tumors (in vivo) are more, or less, sensitive to a particular agent."@en . . "Chemosensitivity volume 1 in vitro assays" . "Electronic books"@en . "Electronic books" . . . . . "Index not Present"@en . "Résistance aux médicaments antinéoplasiques." . . "Drug Screening Assays, Antitumor methods." . . "Drug Resistance, Neoplasm." . . "Cancer Aspect moléculaire Manuels de laboratoire." . . "Biomedicine." . . "Cancer cells." . . "Models, Animal." . . "Cancer Molecular aspects." . . "Tumeurs traitement médicamenteux." . . "Antineoplastic Agents pharmacology." . . "Antineoplastic agents Effectiveness." . . "Cancer Chimiothérapie." . . "Antinéoplasiques pharmacologie." . . "beta-Tocopherol pharmacokinetics." . . "Veterinary Drugs therapeutic use." . . "Medicina" . . "Anticancéreux Efficacité Manuels de laboratoire." . . "Cellules cancéreuses Manuels de laboratoire." . . "Cancer Chemotherapy." . . "MEDICAL Oncology." . . "Neoplasms drug therapy." . . "Oncologia" . . "Cancer Research." . . "HEALTH & FITNESS Diseases Cancer." . .