WorldCat Linked Data Explorer

http://worldcat.org/entity/work/id/1754943023

Resistance to immunotherapeutic antibodies in cancer strategies to overcome resistance

The traditional approaches to treat various cancers include chemotherapy, radiation and/or hormonal therapy. While these therapies continue to be effective in large part, they are not selective and highly toxic. There have been encouraging results in alternative therapeutic approach called antibody-mediated anti-cancer therapy, which is less toxic, more selective, and can also reverse drug/radiation resistance. Monoclonal antibodies or mAbs can be used to destroy malignant tumor cells and prevent tumor growth by blocking specific cell receptors. mAbs can bind only to cancer cell-specific antig.

Open All Close All

http://schema.org/about

http://schema.org/description

  • "The current application of antibody-meditated targeted therapy against cancer has resulted in significant objective clinical responses, prolongation of survival and even cures. More than 20 mAbs have been approved for human use targeting a range of different cancers. However, a major drawback of mAb therapeutics is that a subset of patients does not initially respond and another initially responding subset develops resistance to further treatments. At the present time, there are no effective therapies for these subsets of cancer patients. The analyses of underlying mechanisms responsible for resistance are necessary to develop and generate new targeted therapies that overcome the resistance. Resistance to Immunotherapeutic Antibodies in Cancer: Strategies to Overcome Resistance is a timely volume that deals with various mechanisms of resistance to anti-cancer mAbs therapeutics as well as it deals with novel approaches to overcome resistance. The reviews in this volume are written by highly qualified, established and experienced leaders in the field of resistance to anti-cancer mAbs."
  • "The traditional approaches to treat various cancers include chemotherapy, radiation and/or hormonal therapy. While these therapies continue to be effective in large part, they are not selective and highly toxic. There have been encouraging results in alternative therapeutic approach called antibody-mediated anti-cancer therapy, which is less toxic, more selective, and can also reverse drug/radiation resistance. Monoclonal antibodies or mAbs can be used to destroy malignant tumor cells and prevent tumor growth by blocking specific cell receptors. mAbs can bind only to cancer cell-specific antig."@en

http://schema.org/genre

  • "Electronic books"
  • "Electronic books"@en

http://schema.org/name

  • "Resistance to immunotherapeutic antibodies in cancer strategies to overcome resistance"@en
  • "Resistance to immunotherapeutic antibodies in cancer strategies to overcome resistance"
  • "Resistance to Immunotherapeutic Antibodies in Cancer Strategies to Overcome Resistance"
  • "Resistance to Immunotherapeutic Antibodies in Cancer Strategies to Overcome Resistance"@en
  • "Resistance to immunotherapeutic antibodies in cancer : strategies to overcome resistance"
  • "Resistance to immunotherapeutic antibodies in cancer : strategies to overcome resistance"@en