Audio-visual presentation : Molecular cloning of RyR ; The identification of functional domains ; RyR channel structure ; Channel regulation by: a) inter-RyR interaction, b) divalent cations and c) protein:protein interactions ; The role of leucine zippers in assembling the 'macromolecular complex' ; Defective protein:protein interactions in cardiac disease ; Genetic basis of RyR dysfunction ; Identification of mutations in cardiac RyR ; Functional characterization of RyR mutations ; Investigating interdomain interactions using state-of-the-art imaging tools ; Pathological defects in channel stability.
"Audio-visual presentation : Molecular cloning of RyR ; The identification of functional domains ; RyR channel structure ; Channel regulation by: a) inter-RyR interaction, b) divalent cations and c) protein:protein interactions ; The role of leucine zippers in assembling the 'macromolecular complex' ; Defective protein:protein interactions in cardiac disease ; Genetic basis of RyR dysfunction ; Identification of mutations in cardiac RyR ; Functional characterization of RyR mutations ; Investigating interdomain interactions using state-of-the-art imaging tools ; Pathological defects in channel stability."@en
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