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http://worldcat.org/entity/work/id/2257478362

Treatment of patients with multiple sclerosis a review of guidelines

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http://schema.org/description

  • "Multiple sclerosis (MS) is an unpredictable, often disabling disease of the central nervous system. The disease attacks the myelin, which is a protective covering wrapped around the nerves of the central nervous system. There are four types of MS disease states: relapsingremitting MS (RRMS), primary progressive MS (PRMS), secondary progressive MS (SPMS), and progressive relapsing MS (PRMS). RRMS describes a course of MS characterized by an unpredictable but clearly defined episodes (or exacerbations) during which new symptoms appear or existing ones get worse affecting 85% of MS patients. The hallmark of RRMS is the recovery or remission that occurs between attacks. PPMS describes a course of MS which is characterized by a slow accumulation of disability, without relapses affecting 10% of patients. It may stabilize for periods of time, and even offer minor temporary improvement, but overall, there are not periods of remission in PPMS. SPMS follows on a course of RRMS. Over time, distinct relapses and remissions become less apparent and the disease begins to worsen steadily. About 50% of people with RRMS will develop SPMS within 10 years of diagnosis. PRMS, the rarest course of MS, affects about 5% of patients. People with this form of MS experience steadily worsening disease from the beginning, but also experience clear attacks of symptoms, with or without recovery. MS medications are generally divided into three categories: immunomodulatory therapies, steroids, and medications for MS related symptoms such as fatigue or pain. The goals of MS treatment include improving the speed of recovery from attacks, reducing the number of attacks or the number of MRI lesions, and attempting to slow progression of the disease. However, choosing, initiating, stopping and changing treatments for patients remains a point of controversy among healthcare professionals. As a result, the purpose of this review is to examine the evidence-based guidelines for the treatment of MS and stopping or switching MS treatment."

http://schema.org/genre

  • "Electronic books"

http://schema.org/name

  • "Treatment of patients with multiple sclerosis a review of guidelines"