A study to determine the relative biological effectiveness of neutrons by correlating the physiological changes of the eye to X-radiation
The heads of white albino rabbits were exposed to two X-ray units with differing parameters, and to pile radiation from a critical reactor, using four different moderator thicknesses. Estimations were made of the extent of tissue damage in the eyes by observations of the effects on the electroretinogram, biochemical determinations, histopathological and clinical observations, in the attempt to derive an RBE for acute retinal changes. The RBE derived for thermal neutrons at 24 hours post-radiation varied considerably with the different indicators, but appeared to e not less than 1 and not greater than 3. Higher energy neutrons appeared to have a much higher relative biological effectiveness.
"The heads of white albino rabbits were exposed to two X-ray units with differing parameters, and to pile radiation from a critical reactor, using four different moderator thicknesses. Estimations were made of the extent of tissue damage in the eyes by observations of the effects on the electroretinogram, biochemical determinations, histopathological and clinical observations, in the attempt to derive an RBE for acute retinal changes. The RBE derived for thermal neutrons at 24 hours post-radiation varied considerably with the different indicators, but appeared to e not less than 1 and not greater than 3. Higher energy neutrons appeared to have a much higher relative biological effectiveness."@en
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