"This monograph reports on the largest clinical series to date in which intraoperative radiation therapy (IORT) has been used in multidisciplinary treatment programs for tumors of various sites and differing histological subtype. It represents the product of 5 years' intensive work by physicians active at a leading European institution. The findings are supplemented by a thorough review of the data presented worldwide during the last two decades. This combination of extensive experience and previously published results enables important practical and conceptual aspects of the current status of IORT to be clarified and indicates areas for future development. The results in this book are meticulously presented and focus on the most important features of clinical research reports based on phase I-II studies (toxicity, local tumor control, and survival data). The tumor sites and histologies analyzed are: head and neck cancer, lung cancer, gastric cancer, pancreatic cancer, colorectal cancer, bladder cancer, gynecologic cancer, soft tissue sarcomas of the extremities, retroperitoneal and other central soft tissue sarcomas, Ewing's sarcoma, osteosarcoma, and intracranial tumors."
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