http://worldcat.org/entity/work/id/889368215

Transmissible spongiform encephalopathies scrapie, BSE and related human disorders

This book provides a comprehensive summary of the current status of information on the agents of scrapie, Creutzfeldt-Jakob disease, bovine spongiform encephalopathy and related diseases. Topics covered include current concepts of the nature of the agent, possible genetic variability of the agent, the role of the prion protein gene and linked genes in influencing disease susceptibility and species tropism, biochemical, electron microscopic and molecular biological analyses of proteins and nucleic acids in infected tissues, in vitro approaches to study of the transmissible agents, epidemiological studies of bovine and human spongiform encephalopathies. Topics are presented as a series of review papers prepared by experts in the field. Readers will find here, in a single volume, the most current series of chapters covering many aspects of the field.

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