"Camptothecin analogs & derivatives." . . "Camptothecin analogs & derivatives" . "Tumeurs traitement médicamenteux." . . "MEDICAL Oncology." . . "Camptothecin pharmacology." . . "Camptothecin pharmacology" . "Camptothecin therapeutic use." . . "Camptothecin therapeutic use" . "Cancer Chemotherapy." . . "Camptothecin." . . "Electronic books." . . "HEALTH & FITNESS Diseases Cancer." . . "Krebs (Medizin)" . . "Cancer Chimiothérapie." . . "Medicine." . . . . . . . . . . . . . . . . . . . "Electronic books"@en . "Electronic books" . "Camptothecins in Cancer Therapy"@en . "Camptothecins in Cancer Therapy" . . . . . . . . . . . . . . . . . . . . . . . . . . "Camptothecins in cancer therapy" . "Camptothecins in cancer therapy"@en . . . "This is a critical review of our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer p."@en . . "Chemotherapie." . . "Camptothécine." . . "Antinéoplasiques d'origine végétale." . . "Medicine and Public Health." . . "Antineoplastic Agents, Phytogenic therapeutic use." . . "Antineoplastic Agents, Phytogenic therapeutic use" . "Neoplasms drug therapy." . . "Neoplasms drug therapy" .