This timely guide to kinase inhibitor drug discovery is the first to cover the entire drug pipeline, from target identification to compound development and clinical application. Edited by pioneers in the field, on the drug development side this ready reference discusses classical medicinal chemistry approaches as well as current chemical genomics strategies. On the clinical side, both current and future therapeutic application areas for kinase inhibitor drugs are addressed, with a strong focus on oncology drugs. Backed by recent clinical experience with first-generation drugs in the battle aga.
"This timely guide to kinase inhibitor drug discovery is the first to cover the entire drug pipeline, from target identification to compound development and clinical application. Edited by pioneers in the field, on the drug development side this ready reference discusses classical medicinal chemistry approaches as well as current chemical genomics strategies. On the clinical side, both current and future therapeutic application areas for kinase inhibitor drugs are addressed, with a strong focus on oncology drugs. Backed by recent clinical experience with first-generation drugs in the battle aga."@en
"With Kinase inhibitors being widely seen as the long-sought 'magic bullet' to conquer cancer, this fully comprehensive guide to kinase inhibitor drug development covers the entire drug pipeline from target identification to compound development and clinical application. Volume 1 focuses upon the medicinal chemistry of kinase drugs, from target identification to lead optimization, and contains numerous contributions from large and small pharmaceutical companies. Volume 2 surveys current and future therapeutic application areas for kinase inhibitor drugs, with a strong focus on oncology drugs, as this is the most important therapeutic field for these drugs. In addition, all six currently approved kinase inhibitor drugs (small molecules and antibodies) are described, and their performances in clinical practice are discussed."@en
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