"En los ultimos anos se ha asistido a un cambio en la epidemiologia de la enfermedad invasiva meningococica (EIM) en Uruguay, con disminucion de los casos por serogrupo C y aumento de los casos por serogrupo B. En el ano 2001 se detectaron algunos eventos que alertaron sobre la posibilidad de una epidemia por Neisseria meningitidis grupo B: aumento del numero de casos, desplazamiento de las edades de los pacientes afectados hacia la franja de los mayores de 5 anos, brote epidemico en una pequena ciudad, fallecimiento de pacientes predominantemente mayores de 5 anos y predominio de una cepa (B:4,7:Pl. 15,19) sobre una mezcla de cepas de Neisseria meningitidis grupo B. Se presentan los datos epidemiologicos y microbiologicos que determinaron la decision de inmunizar con la vacuna antimeningococica B-C preparada en el Instituto Finlay a la poblacion de 4 a 19 anos de todo el pais (AU)."@es
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